Thursday, June 30, 2016

Benefits Of A Portable Oxygen Tank


By Lois Evans


If you want to know all about these things, then you would certainly get the information that you are looking for from the paragraphs below. So, be able to take advantage of this source while you still can. If you would do that, then you would certainly be doing yourself a huge favor at this point.

First of all, you will be amazed on how consistent this item will be. Having a portable oxygen tank will be like having your own lifeguard. It will be there at the moment that you start to feel a pain in your lungs. After a while, you will be fine and you will be back to your normal routine and that is great.

Second, refilling an empty tank will never be a problem that you will need to find remedy to. Take note that you have a lot of hospitals in your side of town. If your tank has already reached its critical level, then you just need to go to the nearest institution and you will have once again the thing that keeps you alive.

Third, the oxygen that you will be taking will be regulated all the time. If you do not believe that, then you can talk to someone who already has the equipment that is being featured in here. So, open yourself to the possibility that this item will allow you to continue living the life that you love and that you will be fine.

You can get the additional equipment for free. If you have managed to find a reputable provider, then there should be no problem on this part. You would just have to make the necessary inquiries for you to be sure that you would be getting all of your expectations in here. Never look like a fool in front of other people.

It would not be that heavy to carry. However, since you are most probably sick, then this is something that would most probably benefit your family member instead. Nevertheless, it is still important for you to know about this aspect. It would make you further realize that you are on the right side of the road.

You will have the health condition that you have but you will be more relaxed than ever. That is because you know that nothing grave will happen to you when you get your attacks. You will be safe as ever.

A tank can be pretty affordable too. Remember that you are on a tight budget right now. If you do not like going back to the hospital all the time, then you would just have to be in this path as much as possible. That is how you can keep going with some of your routines.

Overall, simply lean to the facts which have been given in here. They may be a lot to take in but they are truth. You have to be less skeptical for your own sake and that is imperative.




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A Novel Gene Therapy Approach to Treating the Wet Form of AMD The BioFactoryTM From Avalanche Biotech


I originally contacted this company in November 2010, when they were still in “stealth mode” and weren't able to share details about what they were doing. Recently, the company got back in touch to provide an update, having announced, in December 2011, a clinical trial of their gene therapy approach to treating the wet form of AMD.

Since their approach is unique, and possibly “game changing” for the treatment of the wet form of AMD, I asked if I could prepare a writeup about the company and its technology for publication in my online Journal, and the co-founder and CEO Tom Chalberg agreed to answer my questions, as best as he could.

So, here in their own words is what Avalanche Biotech is all about.


The Company

Founded in 2006, as an outgrowth of co-founder Thomas Chalberg’s PhD work in genetics while at Stanford University (along with pioneering work with gene therapy at Prof. Elizabeth Rakoczy’s lab at the Lions Eye Institute in Perth, Australia), Avalanche Biotech is a privately held biotechnology company that develops technologies and products for sustained delivery of therapeutic proteins to the eye to treat wet age-related macular degeneration (AMD), as well as other ophthalmic disorders, such as diabetic retinopathy, retinal degeneration, and glaucoma.

The company was incubated at the Berkeley Entrepreneurship Laboratory at the UC Berkeley Haas School of Business in 2010-2011 while Tom was completing his MBA at that school. The company set up offices in San Francisco’s SOMA district, near the UCSF Mission Bay Campus, in July 2011.

The company’s lead product treats wet AMD by using the body's own cells to produce therapeutic proteins on an ongoing basis after only a single injection. The goal is effective long-term treatment of wet AMD without the burden of frequent, ongoing intra-ocular injections.

In June 2011, Avalanche Biotechnologies licensed additional intellectual property from the University of California, Berkeley, property related to novel adeno-associated virus (AAV) vectors for use with the company's proprietary BioFactoryTM drug delivery platform. A BioFactory™ is a long-term ocular drug delivery technology that secretes a therapeutic protein over years following a single eye injection. The company’s intellectual property includes access to a pipeline of next-generation vectors for non-invasive drug delivery to the retina.

In November 2011, Avalanche began a collaboration with Lions Eye Institute in Perth to commercialize AAV-based approaches, developed using the company’s proprietary BioFactory™ drug delivery platform.


The People – Founders and Management Team


Thomas W. Chalberg, PhD
Co-Founder & Chief Executive Officer

Dr. Chalberg, earned his PhD in Genetics from Stanford University where, as a Howard Hughes Medical Institute Fellow, he focused on retinal diseases and novel technologies for gene therapy. He was interested in retinal diseases, including retinal degenerations and age-related macular degeneration (AMD). During his PhD program at Stanford, he worked with Dr. Mark Blumenkranz, his committee member and a co-founder of Avalanche Biotech, on creating a sustainable solution for sustained delivery of therapeutic proteins to the retina. They were joined by Mitchell Finer PhD, a biotechnology industry expert with experience in gene therapy, and Steven Schwartz MD, an expert in retinal disease and early-stage clinical development.

Prior to joining Avalanche, Dr. Chalberg worked on the ophthalmology team at Genentech, helping to launch Lucentis (ranibizumab by injection), a novel therapeutic for age-related macular degeneration. Dr. Chalberg holds an A.B. from Harvard University, where he graduated magna cum laude and Phi Beta Kappa. He earned a PhD in Genetics from the Stanford University School of Medicine and an MBA from the UC Berkeley Haas School of Business. Tom is a member of the Board of Visionary Scientists for Hope for Vision, a non-profit charity supporting vision research.

Dr. Chalberg joined Avalanche Biotechnologies, Inc. on a full-time basis as President and Chief Executive Officer on October 11, 2010.


Mark S. Blumenkranz, MD
Co-Founder & Director

Dr. Blumenkranz is an ophthalmologist and trained vitreoretinal surgeon at the Byers Eye Institute at Stanford University, where he has served as Chairman of Ophthalmology since 1997. Prior to that, he served on the faculty of the Bascom Palmer Eye Institute in Miami, Florida, and as founder and Director of the Vitreoretinal Fellowship Program at William Beaumont Hospital in Royal Oak, Michigan – two of the top retinal training programs in the United States. His primary clinical interests center on medical and surgical treatment of vitreoretinal diseases, with a specific emphasis on macular problems. Dr. Blumenkranz was also a founding member of the Eyetech Pharmaceuticals Scientific Advisory Board and a founder or director at several Silicon Valley-based biotech startups, including Oculex Pharmaceuticals, MacuSight, Optimedica, and PEAK Surgical. Mark received his B.A. and Master of Medical Science in Biochemical Pharmacology of Brown University and M.D. degree at Brown University followed by a Residency in Ophthalmology at Stanford.


Steven D. Schwartz, MD
Co-Founder & Director

Dr. Schwartz is an ophthalmologist and trained vitreoretinal surgeon at the UCLA Jules Stein Eye Institute, where he serves as Director of the Retina Service. At UCLA, he has served as principal investigator in a number of early-stage clinical trials for retinal diseases, including the initial studies for ranibizumab (Lucentis) and novel products in gene and cell therapy. Dr. Schwartz has held various key positions at Eyetech Pharmaceuticals, and has served on a number of Scientific Advisory Boards, including Genentech, Ophthotech, Optos, and Optimedica. Steve received his B.A. from UC Berkeley and his M.D. from USC School of Medicine, followed by a Residency in Ophthalmology at UCLA and vitreoretinal fellowship at Moorefield's Eye Hospital in London.


Mitchell H. Finer, PhD
Co-Founder & Senior Consultant

Dr. Finer has over 25 years of experience in biotechnology, building and managing companies from discovery through market launch, in addition to pioneering the development of human monoclonal antibodies, and cell and gene therapies. Currently, Dr. Finer serves as a Senior Consultant to Avalanche and is the Chief Scientific Officer of bluebird bio. Previously, he served as senior vice president of development and operations for Novocell (now Viacyte), a stem cell engineering company researching treatments for diabetes and other chronic diseases. Dr. Finer has served as CEO of Intracel Holdings LLC and Genteric Inc., and as vice president of research and development for the Gencell division of Aventis Pharma (now Sanofi). He was also a founder and vice president of research for Cell Genesys Inc., and a founder of Abgenix. Mitch received a B.S. in biochemistry and molecular biology from the University of California at Berkeley and a Ph.D. in biochemistry and molecular biology from Harvard University. He completed a postdoctoral fellowship at the Whitehead Institute for Biomedical Research.


Advisory Boards

On October 1, 2010, Avalanche announced the founding members of its Scientific and Clinical Advisory Board. The Scientific Advisory Board is chaired by Dr. Elizabeth Rakoczy, Winthrop Professor of Molecular Ophthalmology at the Lions Eye Institute, University of Western Australia. Joining her is Dr. Mitchell Finer, Chief Scientific Officer of bluebird bio and a co-founder of Avalanche.

The Clinical Advisory Board will be chaired by Dr. Ian J. Constable, Founder and Professor at the Lions Eye Institute, University of Western Australia. Joining him is Dr. Mark S. Blumenkranz, Chairman of Ophthalmology at the Byers Eye Institute at Stanford, Dr. Steven D. Schwartz, Chief of the Retina Division at the UCLA Jules Stein Eye Institute, Dr. Judy Gordon, a clinical regulatory consultant with extensive experience in ophthalmology products, and Dr. Steven Butler, Consulting Senior Biostatistician.

On September 1, 2011, Avalanche announced the addition of three renowned scientific leaders in academia and industry to its Scientific Advisory Board: Dr. Jean Bennett, F.M. Kirby professor of ophthalmology at the University of Pennsylvania; Dr. Estuardo Aguilar-Cordova, CEO of Advantagene; and Dr. J. Fraser Wright, Director of the Clinical Vector Core at Children's Hospital of Philadelphia. They will join an august group of colleagues on Avalanche's Scientific and Clinical Advisory Boards.


The Technology

The Avalanche Approach

Currently, wet age-related macular degeneration is treated with frequent injections of an anti-VEGF protein directly into the vitreous of the eye, requiring frequent office visits to assess progress and for retreatment injections with the drug, as many as 8-12 retreatments per year. This creates a burden for both patients and physicians, and limits access for those who are not able to comply with frequent visits and injections.

Avalanche’s lead product is AVA-101, currently in clinical testing for the treatment of wet AMD. Following a single injection, AVA-101 creates an Ocular BioFactoryTM that continuously secretes a therapeutic protein over an extended period, avoiding the need for frequent intraocular injections of recombinant anti-VEGF protein. The therapeutic protein is a potent inhibitor of vascular endothelial growth factor (VEGF), a clinically validated target in wet AMD. Drug delivery technology for the Ocular Biofactory™ has been pioneered under the leadership of Elizabeth P. Rakoczy, Winthrop, Professor of Molecular Ophthalmology at the Lions Eye Institute. As of mid-December 2011, Phase I/II clinical trials are in progress to evaluate safety and efficacy of a single subretinal injection of AVA-101 into eyes of patients with exudative age-related macular degeneration (wet AMD).

The Ocular BioFactoryTM

Avalanche has developed a proprietary drug delivery system which uses the body's own cells to produce therapeutic protein on an ongoing basis after only a single injection This, in effect, creates a "BioFactoryTM" in the patient's eye to treat wet AMD.


The Ocular BioFactoryTM


How it Works

Avalanche delivers its therapeutic treatments through the use of a vector made from a small biological nanoparticle called Adeno-Associated Virus (AAV). Humans are commonly exposed to AAV without any known safety issues or association with disease. AAV-based therapies are in development for a wide range of diseases including heart failure, Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS), among others, along with a litany of retinal diseases in addition to the treatment of AMD.

To create a safe therapeutic vector, viral genes are removed from AAV and replaced with specific genes encoding a therapeutic protein that specifically treats AMD. AAV can infect a variety of retinal cell types and remain stable, resulting in long-term therapeutic protein expression in a variety of retinal cell types. In clinical studies, AAV appears safe and well-tolerated when injected into the retina.



The Avalanche Difference

As opposed to the current standard of care, which is effective for a short period of time, the Ocular BioFactoryTM continues to express therapeutic protein, gathering momentum and reaching peak expression after 4-6 weeks. At that point, the treatment continues to be maintained on an ongoing basis. The result is a continuous, steady-state level of therapeutic protein, which eliminates the need for frequent re-injections. Based on preclinical studies, the therapeutic effect will be maintained for at least 18 months and has the potential to last for several years following treatment from a single injection.(1)


Collaborations

Avalanche collaborates with leading academic institutions and pharmaceutical companies to develop and market its drug delivery platforms. We are looking for strategic partnerships with companies focused on ophthalmology and drug delivery for eye disease.

Our Partners Include:

Lions Eye Institute

In 1975 the Lions Save-Sight Foundation (LSSF) established the Lions Chair in Ophthalmology at the University of Western Australia (UWA). Professor Ian Constable AO was appointed to this position and subsequently established the Lions Eye Institute (LEI). As LEI's inaugural Managing Director, Professor Constable spearheaded its efforts to eradicate blindness worldwide. LEI conducts first class scientific research into blindness and incorporates one of Australia's largest ophthalmic practices. The Institute also houses the Lions Eye Bank and the LSSF.

As noted above, Avalanche announced its collaboration with the Lions Eye Institute in November 2011, and its first human clinical trial is being undertaken at the institution.

Merck Sharp & Dohme Corporation

Merck (known as MSD outside the United States and Canada) is a global healthcare leader working to help the world be well. Through prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, Merck works with customers and operates in more than 140 countries to deliver innovative health solutions.

The therapeutic protein used in the Ocular BioFactoryTM is exclusively licensed by Avalanche from Merck Sharp & Dohme Corp, formerly Merck & Co., Inc.


The Clinical Trial

The initial clinical trial, Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration (AMD), NCT01494805, is currently recruiting participants at the Lions Eye Institute, in Perth, Western Australia, and was established on December 14, 2011.

It is a Phase I/II controlled dose-escalating trial to establish baseline safety and efficacy of a single subretinal injection of AVA-101 (rAAV.sFlt-1) into eyes of patients with exudative age-related macular degeneration.

The study will involve 24 patients aged 65 or above who have wet AMD. The patients will be radomized to receive one of two doses of the agent (16 patients) or assigned to the control group (8 patients). Patients in all three groups will be eligible for rescue therapy with ranibizumb (Lucentis). The study is estimated to be completed in three years (December 2014), with a primary completion date of December 2012 (i.e., final data collection for primary outcome measurement). (For more information, please follow the NCT hyperlink above.)


The Future

The company is involved in researching several other therapeutic proteins for the following indications, according to the Clinical Trials and Milestones graphic shown below:



AVA--201 – is in research for the treatment of specific cells in the retina, including possible treatment for rare genetic diseases.

AVA--301 – is in research for the treatment of diseases associated with photoreceptor cells.




Editor’s Comments – As I noted in my introduction, if this approach is successful, it could result in a “game change” in the way wet AMD is treated. Instead of multiple injections to gain control of neovascularization, one injection at the first signs of neovascularization could stop it dead in its tracks and the effect could last, potentially, for several years.

In addition, it is conceivable that patients at risk of developing wet AMD could receive a therapeutic injection of AVA-101 to prevent the occurrence of wet AMD! This would be a definite paradigm shift in the treatment of AMD.

With the human clinical testing now underway, we should have an indication of initial results with this unique approach within about a year.

Stay tuned!


For more on the technical aspects of the company’s technology, please see reference 2.

References:

1. AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness ; Bennett, J., Ashtari, M., Wellman, J., Marshall, K. A., Cyckowski, L. L., Chung, D. C., McCague, S., et al.; (2012). Science translational medicine, 4(120), 120ra15–120ra15. doi:10.1126/scitranslmed.3002865

2. Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates; Lai, et al, Gene Therapy, (10 November 2011) | doi:10.1038/gt.2011.169


Manhattan Migraine Headache Sufferers Can Get Relief Through Chiropractic


By Tabatha Fickel


Although there are countless medications that you can take to alleviate the pain of a migraine headache, none of these are capable of providing long-lasting results. If you want to limit the frequency and severity of your migraines, you should visit the chiropractor offices Manhattan NY locals have access to. This is often the best way to resolve migraines right where they start.

Chiropractic care is primarily focused on improving the health and alignment of the spine. With this structure is properly aligned, the nerves and the brain are able to send messages back and forth to each other efficiently. When they are not, problems can occur. People with poor spinal alignment can suffer from chemical imbalances, sleep troubles and even mood swings.

Physical problems can also arise when subluxations exists. Certain muscle groups have to compensate for spinal subluxations by working a lot harder than they are naturally intended to. The results can include tension in the facial muscles, neck, shoulders and back, which will in turn lead to recurring headaches.

By resolving spinal subluxations, chiropractors are able to alleviate many of the uncomfortable symptoms that these create. They can use manual adjustments to slowly encourage displace vertebrae back into their natural positions. They also have a range of additional therapies that they can employ to expedite this process and provide greater relief.

This type of care takes time. People often sustain subluxations in instant, impact events. Resolving theses injuries, however, is a gradual and progressive effort. Whether you've harmed your back by bending and lifting a heavy item, a slip and fall accident or a car crash, you will likely need a number of office visits in order to gain optimal results.

As subluxations are slowly corrected over time, your migraines will become less intense and much less frequent as well. You will also be given a few tips for correcting any unhealthy life habits that you currently maintain. Your efforts to attain whole-body health can greatly improve your overall well-being and expedite the healing process.




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The Marijuana Plant A Complete History


By Smokey Joe


Cannabis or marijuana is a native cluster of Central and South Asian regions, and its first documented use of marijuana dates to 3000 BC. Many Chinese and Asian relics found in grave sites and burial spots contain marijuana leaves and resin. Apart from Chinese and Eastern Asian regions, Traditional text 'Vedas' speaks of a plant that was worshiped and considered a medical relief 'Soma ' is associated to marijuana by many followers of text. Weed is naturally found in Himalayan Mountain Ranges, and is consumed and exported as a money crop. Areas that are connected with native blow production includes Nepal, India, Kashmir, and Pakistan.

Folks have used marijuana for meditational purposes since ancient times, many Nepali monks still meditate using the plant, which helps them purify their mind and use it for concentration. It is well documented to have been used as a medicinal herb across the history. Its far-reaching use began with exportation of cannabis seeds and plants for medical purposes to Northerly African Area, from where it made its way to Europe. This trade dates back as early as 500 A.D. In the western world it was employed as a source of fiber. Marijuana plants were cultivated in abundance during difficult times of WW2 as the supply of hemp to western world from asiatic sources was halted due to tensions created by the war.

In the 19th century many literary classics mentions marijuana and attempt to describe its psychological facts, the trance it induces and how it is consumed, Les paradis artificiels by Charles Baudelaire and The Hasheesh Eater by Fitz Hugh Ludlow are popular example of such literature.

In the United States, marijuana was employed as a pharmaceutical until 1942, It was used as a prescription drug to ease work pains, queasiness and fits. Many of us used it for its exhilarating effects as well even at that point. A campaign was launched by Drug Enforcement Administration (DEA) that portrayed marijuana use as addictive and a dynamic mind stimulation. This finally gave birth to one of the most sterile disinformation film, Reefer Madness, which was produced by a church group. In the 1950s it was utilized by Beatniks as a stimulant in their own words, while in the 1960s it was used by Hippies as a way to struggle with the government. This was when Buddhist/South Asian influence was high in music and literature of that time, and many of us were rebelling against war and changing a peaceful life-style by meditating with marijuana and Buddhist way of life, the adaption of marijuana use like their Buddhist teachers (as discussed above) was natural.

In 1970s Marijuana was classified a schedule I drug, which basically meant being the most abused drug and no medical use whatsoever. Most of the Marijuana made its way through the south border of United States of America from Mexico, but political pressures and actions by authority ceased the trade to a large extent. In the 1980s Reagan Administration applied a no toleration policy which exterminated all of drug trade from southern borders, which ended in indoor cultivation, California being the hotbed for production. These stringent policies ended in reduced Marijuana use in the late 1980s. Pot was legal in India until 1980s, but it was made illegal by the political pressures by the United States and the administrations firm policies. 1990s once again saw a rise in marijuana consumption, especially among school scholars.

Debates have being triggered since the 1990s about the medical properties and potential usage of the Plant. And since that time, over 15 states in the U. S. have either legalized medical usage of Marijuana or decriminalized it.




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Wednesday, June 29, 2016

How To Choose The Best Body Cleanse


When looking for the best body cleanse, one must consider many facts. This is because conducting such a plan in a safe and careful manner is essential. Detoxification programs are often used for weight reduction or to eliminate toxins from a person's body. Detox is the shortened form of the word, and essentially means the elimination of chemicals and other harmful compounds from a person's liver, intestines, bloodstream and kidneys. This is accomplished by the person adhering to a stringent diet plan.

There are numerous cleansing diet options, ranging from those that are quite restrictive, to those which offer the dieter a little more freedom with regard to his or her food choices. The following are some examples of popular detox programs. However, it is always wise to check with a doctor prior to beginning any new diet.

The most basic of all detoxification plans involve a three day fast, which starts off the diet. Throughout these initial 3 days no food is eaten, and the dieter consumes only water, and no diluted drinks such as tea or coffee. At the end of the fast, one must follow a monotrophic diet for an additional ten days. A monotrophic diet plan involves eating only one type of food at each meal, which is generally fruit of some kind.

A person may also decide to go on a 10-day detoxification program. Such plans are usually focused on eliminating toxins from the colon. Processed and fried foods, as well as alcohol, caffeine, salt, sugar, oil and fats are strictly forbidden. The program lasts for ten days and a very restricted diet is followed during this time. The menu consists of filtered water, vegetables, fruits, organic maple syrup, sea salt, cayenne pepper, and organic lemons.

Many detox program enthusiasts favor raw food diets. Unlike numerous weight reduction or detoxification plans that produce fast results, a raw food detox diet is a slower process. However, it frequently leads to lifestyle changes that are both healthy and permanent.

Raw foods are natural foods that contain no chemicals or preservatives, therefore processed foods and junk foods are prohibited on this plan. The program is said to eliminate up to 90% of the toxins in a person's body in approximately one month.

Numerous nutrition experts are of the opinion that constant exposure to chemicals and preservatives in food and pollutants in the air are the cause of many conditions such as excess weight, skin problems, headaches and fatigue. Those who follow detoxification diets believed that the eradication of such toxins will rebalance one's system to a natural, healthy condition. In addition, it is commonly thought that such diets speed the metabolism and curb the appetite.

As is the case with most health plans, the popularity of inner body cleansing has surged and diminished over the years. However, most nutritionists agree that there are benefits associated with such programs if they are followed responsibly. If one is unsure of which is the best body cleanse, he or she should seek the advice of a physician.




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Yoga for Healthy Aging is Not Science Fiction A Real Life Mission Statement


by Nina 
Field of Mars by Marc Chagall*
“As more people are living longer and fewer are dying young from diseases caused by infections or insufficient food, exponentially more middle-aged and elderly people are suffering from chronic noninfectious diseases that used to be rare or unknown.” —Daniel Liberman

I’m just finishing up the Mars trilogy by Kim Stanley Robinson, a science fiction epic that takes place in the near future about the very first human settlers on Mars. The series spans a period of about 200 years, and several characters you meet at the beginning of the series are still alive at the end. When these characters are in their seventies and eighties, a longevity treatment is developed by Mars scientists that allows the original Mars settlers to continue to live active, healthy lives for an unknown amount of time. Although these characters do develop certain long-term memory problems (mostly about their middle lives), they continue to do productive scientific work, are energetic, physically fit and disease free, and even have active romantic and sex lives. Near the end of the series, a few of them die quite suddenly, not of any long, lingering diseases but very quickly of heart failure. And that seems to be the end that most, if not all, of them, will be facing.

Oh, if only old age was really like that, right? But this science fictional scenario actually exemplifies the very issues I wanted to talk about today. For when we talk about “healthy aging” on our blog, Sax, Nadia, Ann, Coyote, Michel, Maya and others in the Mars trilogy are ideal role models, not because of how long they live but for how healthy, physically active, and intellectually engaged they remain until the ends of their lives.

Lifespan. I guess this is rather obvious, but our “lifespan” is the period of time during which we are alive. But that lifespan could include any number of years spent in poor health. Sax, Nadia, Ann, et al in the Mars trilogy don’t have problems with ill health because in their science fictional world modern medicine can fix almost everything (although one man does die of leukemia). But here in the real world there are many medical conditions that just can’t be cured yet.

Morbidity. Right now, although our lifespans in first world countries have increased significantly due to better nutrition and modern medicine, as Daniel Liberman said in the quote above, middle-aged and elderly people in first world countries can suffer many years of ill health before they die. Lack of exercise, poor eating habits, and stressful lifestyles cause heart disease, strokes, diabetes, osteoporosis, and other chronic problems. This period of ill health during your lifespan is referred to as morbidity.

Now let’s do a little bit of very simple math:

Lifespan – morbidity = health span

Health Span. To put it in words, your “health span” is equal to your lifespan minus the amount of time you spend in ill health. This is the period in your life during which you are generally healthy and free from serious or chronic illness. For the people in the Mars trilogy, since they are very healthy until they suddenly die of heart failure, their health spans are very close to the length of their lifespans. But I’m sure in real life we all know people who live for years in a very debilitated state, perhaps in a nursing home, and I think we can all agree is not a future we would want for ourselves, if we can help it. (See Longevity vs. Morbidity for information about the epidemic of morbidity in the first world.)

So, to be clear, when we talk about yoga for “healthy aging,” we’re not talking about yoga for increasing your lifespan or your longevity. We’re talking instead about doing what you can to keep your health span as long as possible. And while you are makiing your health span as long as possible, we hope you'll also be making the period of time you spend in ill health near the end of your life as short as possible (this is called "compressed morbidity").

And, yes, we believe that yoga can help with this. Our mission here at YFHA is to explore all the ways that yoga can help foster your physical, mental, and emotional health during your lifespan (see Opening Your Yoga Toolbox). And because we’re not living in a science fictional universe, we must acknowledge that there will be times when ill health is unavoidable. But yoga has sometime valuable to offer you during those times as well, including both spiritual wisdom to guide you and tools for cultivating equanimity that will help see you through hard times.

This is all pretty basic stuff, but it’s worth saying because we want to set realistic expectations. We’ve certainly seen prominent new age health gurus out there claiming that you can “reverse aging,” choose your “biological age,” or “change your relationship with time” with yogic practices. But that really is science fiction. And here in the real world you deserve more than that.

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Meeting Death at the Front Door


by Nina 

by Melina Meza
"Research shows that most Americans do not die well, which is to say they do not die the way they say they want to — at home, surrounded by the people who love them. According to data from Medicare, only a third of patients die this way. More than 50 percent spend their final days in hospitals, often in intensive care units, tethered to machines and feeding tubes, or in nursing homes.” —Dan Gorenstein from “How Doctors Die”

Yesterday I heard a very moving piece  How Doctors Die on NPR that made me think again about an issue close to my heart: being able to face death with courage.

My mother died of breast cancer at age 85, and she was able to die with hospice care at home without any invasive procedures, any time in a nursing home or being “tethered” to any machines. Because I was talking to her doctors for her and coordinating her care, I can testify that this was only possible because my mother was clear-eyed about her condition and was willing to admit she had a terminal condition. In fact, one of the requirements for beginning hospice care is for the patient to agree to no more potentially “curative” treatments (hospice provides comfort care only). So this means being willing to face the fact that you are dying.

The piece on NPR and the companion piece in the New York Times article How Doctors Die: Showing Others the Way made the same point. The doctors in the article were able to choose the way they died—and lived while they were in the process of dying—because their medical knowledge helped them face the truth of their situations. Realizing that her condition had become terminal, Dr. McKinley decided to turn down more treatment and to begin hospice care.

"What Dr. McKinley wanted was time with her husband, a radiologist, and their two college-age children, and another summer to soak her feet in the Atlantic Ocean. But most of all, she wanted “a little more time being me and not being somebody else.” So, she turned down more treatment and began hospice care, the point at which the medical fight to extend life gives way to creating the best quality of life for the time that is left."—Dan Gorenstein

While some people do very much want to die in a hospital, I believe that most of us do not. And to make that happen, either for ourselves or for our loved ones, we must be as clear-eyed and honest with ourselves as my mother and the doctors portrayed by NPR and the New York Times were. That takes a lot of courage.

"BRAVE. You hear that word a lot when people are sick. It’s all about the fight, the survival instinct, the courage. But when Dr. Elizabeth D. McKinley’s family and friends talk about bravery, it is not so much about the way Dr. McKinley, a 53-year-old internist from Cleveland, battled breast cancer for 17 years. It is about the courage she has shown in doing something so few of us are able to do: stop fighting." —Dan Gorenstein

How can yoga help you be brave? Of course I can’t write about my own death, but I did help both my parents die at home (and have all the clear-eyed conversations that entailed), so I know it is a very stressful process. So I expect that stress management, of whatever kind works for you, would be valuable. I tried to stay as calm as possible when I was helping my mother and found myself every day doing very long sessions of Legs Up the Wall pose combined with breath work (extended exhalation). And sometimes when I’m doing my breath work these days, I consider that this is a practice I will probably have access to until the very end. For information on various options for stress management, see The Relaxation Response and Yoga. Anxiety—which is fear of things to come—can also be a problem, and yoga can help soothe you when you’re anxious. Baxter and I have done a whole series of posts on anxiety, so see Yoga Solutions for Anxiety and check the index on the right side of the blog under the label "anxiety."

I also hope that yoga philosophy will come to my aid. The Yoga Sutras actually describes abhinivesha or “clinging to life” as one of the impediments to samadhi, describing it as inherent tendency.

Yoga Sutra 11.9 [The tendency] of clinging affects even the wise; it is an inherent tendency.  —trans. by Edwin Bryant

But the Yoga Sutras also tells us that truthfulness (the yama satya) is a crucial part of yoga practice. This is one aspect of the universal “great vow” that is the second branch of yoga.

Yoga Sutra 2. 36 When one is established in truthfulness, one ensures the fruitions of actions. —trans. by Edwin Bryant

And it seems that truthfulness—being willing to hear the truth as well as to tell it—will help you face your death and die the way you want to, and to be able to help your loved ones as they die. Just the other day a friend told me how she was trying to help a friend of hers who was dying. “But he won’t admit it to himself,” she told me. “And that makes it impossible for his friends to help him."

So it's my feeling that you have face the truth yourself. That you have to tell your family the truth. That you have to insist your doctors—and your loved ones—tell you the truth. And if you are helping someone else who is dying, facing the truth about their condition will allow you to provide them with the help they need.

In the audio version I heard, Dr. McKinley called her approach to her impending death as “Meeting Death at the Front Door.” Besides being able to do the things you love as you age (see Being Able to Do What You Love), isn’t an essential part of healthy aging being able to die the way you want?

"The front door at Dr. McKinley‘s big house was wide open recently. Friends and caregivers came and went. Her hospice bed sat in the living room. Since she stopped treatment, she was spending her time writing, being with her family, gazing at her plants. Dr. McKinley knew she was going to die, and she knew how she wanted it to go.

“It’s not a decision I would change,” Dr. McKinley said. “If you asked me 700 times I wouldn’t change it, because it is the right one for me.”


Dr. McKinley died Nov. 9, at home, where she wanted to be.
" —Dan Gorenstein


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How To Best To Find A Dentist For Wisdom Teeth Removal


By Miranda Hawkins


It is natural to get scared. When you are scared, find the courage. The dentist should also be able to assure you that everything will be fine. The reason why you are doing all these checks is because you want to be handled by a competent dentist. Know that the professional fees of dentists vary. It varies from dentist to dentist.

There could be some negative impact which may lead to death in worst scenarios. Thus, it is very important to connect with certified and competent dentists. There are dentists whose expertise is geared towards cosmetic dentistry. This is different from the regular wisdom teeth removal Mauithat most people know.

This has something to do with enhancing the features of the teeth for aesthetic purposes. Dental doctors are also employed by other dental clinics or hospital. Check out the medical institutions that they are affiliated with. The kind of organization that they are in affiliation with determines the kind of dentists that they are. Wailuku, HI is an ideal place of dwelling.

They have to acquaint themselves of the latest development. They have to make sure that they are still relevant in the professional world by taking up further studies. Check with other people. They might be able to recommend a few good dental clinics that they know. Check how their dentist is. You might utilize their dentist for the procedure that you need.

Even if there is a need to conduct the procedure, there must be consultation first. The dentists will have to check you up and interview you about the situation. After which, he will be able to determine what medical procedure is needed to be done on you. Find out if they have gone in with this doctor before. Know the professional fee of the dentist.

They have trained eyes. They are trained to detect abnormalities and other complications in your gums.The corrective measures and treatment should be administered right away. The condition does not have a change of progressing if it is diagnosed early. Prevention is better than cure and this is true.

The receptionist knows the schedule of the dentists. He books appointment for the doctor. Call the receptionist and he should be able to answer most of your questions related to the dental services that they are offering and the doctor. It is good to ask friends and relatives because you are acquainted with these people.

Check the credentials of the dentist. You have to verify the information that you get about the dentist. There are many dental malpractice happening out there. It endangers the lives of people. Dental complications due to negligence can also lead to risk in health and even death.

He should be one who is competent. Make sure that your dentist is a certified professional in dentistry. Know the specialization of your dentist. Know that dentists have different specializations. They need to specialize in the different areas of dentistry.




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Wordless Wednesday Perfectionism


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Lets Talk About Homeopathy!



And Skepticism Surrounding The Great Science!

Hi friends! You must be wondering what I am up to today. You all know about homeopathy and/or are interested to know about this wonderful science and I am sure you are aware of the basic facts about this science of healing. Then why this “Let’s talk about Homeopathy” again?

Well, firstly my love for this science is not limited to earning livelihood and it is “larger than life” for me. Secondly, blogging is a kind of catharsis to me where I can share what I feel with the larger community outside and feel good about it. But this is not all. Many will agree with me that knowing and learning about new things, new sciences, and new ways of life is fascinating. Reading about them makes you aware about your own science in better way and also creates greater level of tolerance to other sciences. But when I keep reading some skeptic comments about my science, that is, Homeopathy, I feel good. Why?

In Marathi we have a saying that says, “Nindakache ghar asave shejari” (It means- critic’s or skeptic’s house should be besides your house). What does that mean? It means that when you have a critic or skeptic besides you talking negatively about you, you have all the reason to ignore him and do what pleases you. It also indicates that the reasons and goals that are close to your heart should be studied in greater depths to shut the mouths of skeptics. Anyway, we are benefited. After all, work speaks far louder than words!

I completely agree with Dana Ullman’s (a great proponent and instructor of homeopathy) views expressed in his blog. He says- “advocating for or using homeopathic medicines does not preclude appreciation for or use of selective conventional medical treatment. Advocates of homeopathy simply honor the Hippocratic tradition of "First, do no harm" and therefore seek to explore and utilize safer methods before resorting to more risky treatments. This perspective has historical and international roots, and it is thus no surprise that American health care which has been so resistant to homeopathic and natural therapies in its mainstream institutions is presently ranked 37th in the world in the performance of its health care system.(1) In comparison, the number one ranked country in the world is France, a country in which around 40 percent of the population uses homeopathic medicines and around 30 percent of its family physicians prescribe them (2)."

One simple fact is that unless homeopathic medicines worked, it would never have such a huge fan following. One thing here I want to ascertain that skeptics would help homeopathy grow. Rather, they are doing it by spreading the word about it. When people read about negativism, they are certainly not fools to agree to any and all comments that are passed about anything. Such derogatory comments make them think more and delve deep into the matter that is being talked about, and I must say that is the reason behind growth of homeopathy.

Any human being with the gift of “thinking capability” has conscience. This conscience is a great thing that can move mountains. It is defined as ability to differentiate between good and bad. Let’s hope that at least where it comes to “health” of the world as whole, skeptics will pay attention to what is right and what is wrong and seek shelter of wisdom, knowledge, and open mindedness. Skepticism is like stress. If it is taken in right perspective, it helps discover newer avenues to existing sciences. But if it exceeds its limit, it leads to closed minds that are not open to learning new things and imbibing right values.

“Health Industry” as a whole should work on the basis of selfless “give and take” relationship. It should harbor interests of people those are sick and want to fight back. Well, to some, this may seem pretty difficult in this world of materialism but everything has its time and I am very optimistic that one day, we all will walk hand-in-hand for the betterment of humanity! Amen!